REDWOOD CITY, Calif., July 22, 2025

InterVene, Inc., a medical device company pioneering interventional devices for venous inflow and outflow obstructions, announced today that the first patient has been treated with its Recana® Thrombectomy Catheter System for venous in-stent restenosis (ISR). The Recana® System is the first fully integrated mechanical thrombectomy system designed specifically to address the long-term complications of venous disease, including ISR and native vein obstructions. The case was performed at University Hospital Galway in Galway, Ireland, by Dr. Gerry O’Sullivan, consultant interventional radiologist.

“The long-term sequelae of venous obstructions, whether in-stent or native vessel, are a devastating consequence of deep venous thrombotic disease. There remains a considerable gap in effective interventional treatments for physicians and their patients living with persistent symptoms related to venous outflow obstructions,” said Dr. O’Sullivan. “I had previously tried and failed to recanalize this patient’s vessels on four separate occasions. Recana® succeeded in just one. This technology offers real promise for patients with limited treatment options.”

ISR is a common and challenging complication of venous stenting, typically managed with balloon angioplasty or stent relining – both of which are suboptimal for restoring and maintaining long-term patency.^1,2

Every year, millions of patients are affected by the long-term complications of deep venous obstructions, experiencing persistent symptoms such as leg pain, swelling, skin discoloration, and in the most severe cases, venous leg ulcers.^3,4